Novel HIV combination therapies could prevent viral escape and rebound

Submitted by Shane D Debolt on July 25, 2022 - 9:58am

This image, taken by a scanning electron microscope, shows a human H9 T cell infected by HIV.National Institute of Allergy and Infectious Diseases

UW News has just posted a story about new research on HIV therapies by Dr. Armita Nourmohammad, an assistant professor of physics here at the University of Washington, and collaborators in Germany.

In a paper published earlier this week in eLife, Dr. Nourmohammad and her colleagues report that carefully designed cocktails of broadly neutralizing antibodies, or bNAbs, could help treat HIV while minimizing the risk of the virus evolving to “escape” treatment. Their study shows that computational approaches to selecting combinations of bNAbs based on viral genetics could help prevent viral escape, making HIV treatments more effective.

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Novel HIV combination therapies could prevent viral escape and rebound